Intelligence pillar
Scientific Safety
Know whether the product is scientifically supportable.
ToxIntel® · by Aᴳ
Enterprise Product Safety Intelligence.
One platform connecting scientific safety, regulatory intelligence, product stewardship, claims, retail readiness, and enterprise risk.
Scientific review signed by Aᴳ — the Agyekum Group.
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See ToxIntel in action.
See how scientific safety, regulatory intelligence, product stewardship, claims, retail, and enterprise risk connect within one governed platform.
Six intelligence pillars
Science → Regulation → Stewardship → Claims → Retail → Risk.
ToxIntel® is one cross-industry system for enterprise product safety. These six pillars are shared core infrastructure — applied through industry-specific workflows in each vertical we serve.
Intelligence pillar
Regulatory Intelligence
Know where the product can be marketed and what requirements apply.
Intelligence pillar
Product Stewardship
Manage safety and compliance throughout the product lifecycle.
Intelligence pillar
Claims Intelligence
Know whether product, scientific, and environmental claims can be substantiated.
Intelligence pillar
Retail Intelligence
Know whether products meet retailer-specific requirements.
Intelligence pillar
Enterprise Risk
Identify emerging scientific, regulatory, litigation, and portfolio risks.
Built for cross-functional teams
Regulatory Affairs, Product Stewardship, Toxicology, R&D, Quality, Legal, Marketing, Sustainability, and Executive Leadership — operating from one scientific system of record.
Regulatory AffairsProduct StewardshipToxicology / Product SafetyR&DQualityLegalMarketingSustainabilityExecutive Leadership
Across the entire product lifecycle
Innovation → Formulation → Safety → Regulatory → Claims → Retail → Market → Post-Market Governance. One connected scientific-intelligence layer, from concept to the shelf and back.
Business outcomes
What enterprise teams actually get.
◆Reduce duplicated scientific work
◆Identify portfolio risk earlier
◆Accelerate product-safety decisions
◆Maintain institutional scientific knowledge
◆Improve retailer readiness
◆Strengthen claims substantiation
◆Monitor regulatory change
◆Create defensible scientific governance
Consultancies & scientific service providers
Enterprise infrastructure for scientific consultancies.
Regulatory consultancies, toxicology practices, and product-safety service providers use ToxIntel as governed infrastructure — to increase consultant capacity, standardize workflows, preserve institutional knowledge, and deliver work under their own brand through white-label deployment and enterprise APIs.
Increase consultant capacityStandardized workflowsPreserved institutional knowledgeWhite-label deploymentEnterprise APIs
Reference
Safety & compliance terminology.
Definitions from the industry verticals where ToxIntel is deployed today — most mature in Beauty & Personal Care, applied through the same shared core infrastructure across every other vertical.
Cosmetic Safety Assessment
Comprehensive evaluation of cosmetic and personal care products to confirm they pose no risk to human health under normal and reasonably foreseeable conditions of use. Each assessment aligns to global standards (EU 1223 Part A & B, MoCRA, FDA, Health Canada), providing the scientific foundation for market entry, retailer onboarding, and regulatory defensibility.
Toxicological Risk Assessment (TRA)
Formalized hazard-and-exposure evaluation that quantifies the toxicological burden of each ingredient at the formulation level. We derive Points of Departure (PoD), apply route-specific uncertainty factors, and produce defensible Margin of Safety (MoS) calculations suitable for retailer review and regulatory submission.
Quantitative Risk Assessment (QRA)
Data-driven derivation of safe exposure thresholds — essential for sensitizers, fragrance allergens, and ingredients with dose-response endpoints. Our QRA models follow IFRA, SCCS, and OECD guidance to ensure formulas remain within scientifically validated safety boundaries across leave-on and rinse-off product categories.
Exposure-Based Risk Modeling
Dynamic modeling of how consumers actually interact with a product. We factor application area, daily frequency, retention factor, age cohort, and skin condition to calculate precise systemic exposure dose (SED), localized exposure, and aggregate cross-product exposure where relevant.
Ingredient Screening
Proactive evaluation of every raw material against global restricted substance lists, emerging chemicals of concern, and proprietary reliability tiers — before formulation begins. Outputs include risk-ranked ingredient profiles, alternative recommendations, and supplier-readable rationales.
Pregnancy & Breastfeeding Evaluations
Specialized toxicological reviews focused on reproductive, developmental, and lactation endpoints. We provide the scientific substantiation needed to address vulnerable consumer populations with confidence, including endocrine activity flags, placental transfer considerations, and clear use-during-pregnancy positioning.
Retailer Readiness Documentation
Turnkey compliance dossiers tailored to the specific scientific and documentary expectations of Sephora Clean, Credo Standard, Whole Foods Premium Body Care, Target Standards, and Ulta Conscious Beauty. We translate complex toxicological data into the exact formats demanded by each marketplace.
Product Safety Intelligence
Beyond compliance, ToxIntel delivers strategic intelligence — anticipating regulatory shifts, retailer policy updates, and consumer expectations. Each output is engineered to remain a trusted reference across the product lifecycle.
Regulatory Toxicology Support
Expert navigation of global chemical regulations: MoCRA (US), EU Cosmetic Regulation 1223/2009, Health Canada Cosmetic Notification, ASEAN harmonization, and California Proposition 65. We bridge scientific safety data with the legal compliance language required across jurisdictions.
Claims Substantiation
Scientific validation of safety and efficacy claims — from "dermatologist-tested" and "non-comedogenic" to "pregnancy-safe" and "free-from." We assemble the objective evidence required to defend marketing language against regulator and class-action scrutiny.
MoCRA Readiness
Operational alignment with the Modernization of Cosmetics Regulation Act. Adverse event reporting frameworks, safety substantiation files, responsible person designation, facility registration, and ingredient statement workflows — all delivered as audit-ready artifacts.
Supplier & Ingredient Governance
End-to-end oversight of the chemical supply chain. We help establish supplier safety standards, conduct raw-material reliability reviews, and provide ongoing governance so consistency and compliance are maintained at the source — not discovered downstream.
Comprehensive evaluation of cosmetic and personal care products to confirm they pose no risk to human health under normal and reasonably foreseeable conditions of use. Each assessment aligns to global standards (EU 1223 Part A & B, MoCRA, FDA, Health Canada), providing the scientific foundation for market entry, retailer onboarding, and regulatory defensibility.
Frequently asked
Common questions.
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